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If needed for a clear medical indication (such as treating pellagra in a pregnant patient), niacinamide can be used with caution, but unnecessary high-dose B supplementation is avoided in pregnancy

QUESTION See Answer What precautions should you take with vitamin B12 shots

Track your own progress rather than measuring against others

Unfortunately, NAD+ levels decline with age, stress, poor diet, and metabolic dysfunction

Keep in mind that B-complex supplements can contain eight water-soluble vitamins, including: B1 (thiamine) B2 (riboflavin) B3 (niacin) B5 (pantothenic acid) B6 (pyridoxine) B7 (biotin) B9 (folate/folic acid) B12 (cobalamin) Tips For Safe Supplementation 1

Thiamine has not been associated with fetal harm