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Retatrutide is more accurately described as a triple receptor agonist research compound involving GLP-1, GIP, and glucagon receptor pathways

This case underscores the potential for tirzepatide to cause severe gastrointestinal dysmotility and fecal stasis, highlighting the importance of vigilance for bowel complications in patients on GLP-1 RAs who present with acute abdominal symptoms [15]

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Many patients notice that semaglutide reduces cravings for sugary or highly processed foods before it significantly reduces overall hunger

doi:10.2337/dc18-2028 Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, et al