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Images comparing brain responses to the first dose of nicotine and to the fifth dose given four days later illustrate the dramatic changes in brain function in areas such as the anterior cingulate gyrus and hippocampus

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My grandfather was an inveterate pipe smoker, and his preferred brand was always Erinmore Flake (I never, in 20 years saw him with anything else on his mantelpiece), but I have a bit of memory dissonance that I need to sort out

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