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Among regular drinkers, consumption plummeted from 23.2 to 7.8 units per week a 68 percent reduction, which Professor le Roux noted is comparable to that achieved by nalmefene, a drug used to treat alcohol use disorder in Europe. The potential for these weight loss drugs to reduce alcohol consumption could yield additional public health and economic benefits

While it is well-established that intestinal GLP-1 cells can exert influence through paracrine mechanisms, recent evidence suggests the possible existence of synaptic-like connections between GLP-1 cells and peripheral neurons, including those of the vagus nerve

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Clarkson admits she "wasn't shocked" when she heard about her condition.

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