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Perimenopause brings hormonal shifts that trigger weight gain in up to 70% of women

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GLP-1 secretion is stimulated by nutrient intake and exerts its effects on glucose homeostasis by stimulating insulin secretion, gastric emptying confiding the food intake, and -cell proliferation

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One of the largest real-world analyses in T2DM More than 64,000 participants Evaluated a practical "everyday clinic" decision rather than an idealized RCT scenario Compared therapy intensification versus complete therapeutic switch Reflected real-world dose titration patterns and clinician behavior

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