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In the search for this prophesised molecule, Dr Joel Habener and his team at Massachusetts General Hospital decided in the late 1970s to study glucagon, another hormone produced by the pancreas that has an opposite action to insulin and increases blood glucose levels

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Hydration is also critical

Taking medications with smaller, low-fat meals may help (except for oral semaglutide/Rybelsus, which requires administration on an empty stomach with water only, at least 30 minutes before food, beverages, or other medications)

Role of SGLT-2 in T2DM Each day, approximately 180 grams of glucose is filtered in the kidneys of a normal healthy adult

Medical writing support was provided by Aarti Shah and Nicole Westerholm of AXON Communications (funded by Novo Nordisk A/S)