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If severe, slower dose escalation may be needed, potentially extending the timeline to therapeutic benefit

Theyre increasingly showing up to retail stores and restaurants seeking out healthy food and drink options to reach wellness goals, and as these drugs continue to become more mainstream and more part of consumer consciousness, retailers and brands really have to be looking at GLP-1 as somewhat of a leading indicator of this larger cultural phenomenon, and looking for ways to innovate and reach this growing population of consumers who are looking for healthy benefits from the products they buy. Joyner shared the change in monthly sales during the first year of active GLP-1 use in various outlets: Convenience stores: down 5.2% Mass: down 3.9% Dollar: down 1.1% Traditional grocery store: down 1% Food, natural: down 0.5% Drug: up 1% Club: up 2% Food, value grocery: up 5.6% Pure-play e-commerce: up 8.2% The report said that on average, households with GLP-1 weight-loss users typically spend more on CPG food, beverages and foodservice before they even initiate use of a GLP-1 than nonuser households, a trend that continues even in the first year of GLP-1 use

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doi: 10.1523/JNEUROSCI.4703-13.2014 99 GongNFanHMaANXiaoQWangYX

Announcing the collaboration in 2023, GE HealthCare said peripheral focused ultrasound therapy which uses ultrasound to activate the nervous system, stimulating nerve pathways to produce effects such as increased glucose metabolism has potential as a non-invasive, non-pharmacological alternative for chronic disease management