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Gallbladder Events : Cholelithiasis and cholecystitis have been observed at slightly higher rates, likely related to rapid weight loss rather than a direct drug effect

Research on tirzepatide and body composition shows that approximately 75% of weight lost is fat mass and 25% is lean mass

GLP-1 Availability in Canada: Current Supply and Cost Barriers Brand-name semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro) remain tightly rationed across Canada's provincial health systems

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