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Description
Gastrointestinal Side Effects and Gut Motility Changes The most commonly reported side effects include nausea, vomiting, diarrhea, constipation, and abdominal discomfort

[25 (1.5%) ischaemic and 2 (0.1%) haemorrhagic] vs

Although the achieved level of glycemic control differed between groups (7.8% vs 8.2%), this small difference seems unlikely to fully account for identified benefits

A potential additional advantage of GIP is the protection against hypoglycemia since GIP infusion is accompanied by a decreased need for further glucose administration to maintain a satisfactory glycemic level during an insulin-induced hypoglycemic clamp [15]

Clinical trials show patients on metformin who added tirzepatide achieved 9-11 kg weight loss over 40 weeks, substantially more than metformin's typical 1-3 kg reduction alone

Which medication should you choose based on side effects
