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Description
FEBS Lett
Cleavage of GCLC occurs at Asp 499 within the sequence AVVD 499 G, which is located upstream of Cys 553 thought to be important for disulfide bond formation with GCLM [35,45]
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2022;119:e2117396119
What is Epitalon
A proximal AP-1 element (263 to 269) was found to be critical in mediating the effect of oxidative stress-induced increase in human GCLC transcription [98103]
