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Similar content being viewed by others Introduction Glucagonlike peptide 1 receptor agonists (GLP1RAs) are a cutting-edge anorectic therapy option with growing popularity

doi: 10.1210/jc.2010-2081 [DOI] [PubMed] [Google Scholar] 39

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Novo Nordisk Announces FDA Approval of Label Update for Rybelsus (semaglutide) Allowing Use as a First-Line Option for Adults With Type 2 Diabetes

In the VTA, GLP-1R activation via central administration of GLP-1RAs such as exendin-4 modulates neuronal excitability, in part by enhancing AMPA/kainate receptor activity on glutamatergic inputs and by regulating local GABAergic interneuron tone [10,23]