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Here, we report on the identification of a gene that is conserved from C

Weight management/metabolic effects: GLP-1 RAs may also support weight management in adults with type 2 diabetes who are overweight or obese, providing an added metabolic advantage alongside their primary glycaemic and cardioprotective effects

Outlook The GLP-1 agonists are an impressive new option for weight loss, especially in the setting of type 2 diabetes due to their glucose-lowering benefits

33 When GLP-1 binds to its receptor on alpha cells, it triggers intracellular signaling pathways that increase cAMP levels, initiating processes that suppress glucagon synthesis and release