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Description
Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2 4 mg for weight management: a randomised, controlled, phase 1b trial

It remains an investigational compound in Phase 3 clinical development

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Chronic, unmanaged GERD (heartburn more than twice per week for several weeks) can lead to esophagitis, Barrett esophagus, or esophageal strictures over time

Fat tissue produces estrogen, so significant weight loss changes estrogen levels
