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Neuroendocrinology 2011;94:291301 [DOI] [PubMed] [Google Scholar] 36.Spranger J, Gundert-Remy U, Stammschulte T

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The effects of exogenous GLP-1 observed after administration to patients with type 2 diabetes (11) include: Decreased glucagon concentrations Improved insulin sensitivity Decreased A1C Slowed gastric emptying Increased satiety Decreased free fatty acid concentrations Decreased body weight However, the therapeutic use of native GLP-1 is limited by its very short half-life and rapid degradation

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Stiede K, Miao W, Blanchette HS, Beysen C, Harriman G, Harwood HJ Jr, et al
