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(10) Cigarette smoke is known to deplete the cellular glutathione pool in the airways, exacerbating oxidative damage and inflammation in the lung, which is likely the reason why smokers with COVID-19 more likely require intensive medical interventions

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Each biological sample was run in triplicate

Interestingly, while mitochondrial transplantation led to sustained increases in ATP production and OCR in P301L SH-SY5Y cells, the MMP returned to its baseline level after 48 h