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doi: 10.1074/jbc.M400600200

Competing interests A.J.S

Despite literature touting GLP-1s as long-term treatments, prescribers have indicated to Urick that patients often only use the drugs to reach certain weight loss goals and then discontinue treatment once these are accomplished

A critical consideration is that diabetes itself substantially increases gastroparesis riskaffecting up to 5% of patients with type 1 diabetes and 1% with type 2 diabetes

Reimbursement for obesity-focused GLP-1 therapies remains inconsistent, particularly for oral formulations indicated for obesity management

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