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[Abstract] INS-1 cells are incubated with THAP (0.5 M), H89, with Exendin-4 or FSK at indicated concentration for 24 h, then the IL-1 level is analyzed by qRT-PCR (n = 3)

Its endogenous form has a plasma half-life of only 2-3 minutes due to rapid degradation by dipeptidyl peptidase-4 (DPP-4) and renal clearance

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