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Human-focused reviews and meta-analyses have debated the magnitude and clinical relevance of lean mass changes during GLP-1RA therapy [41], whereas preclinical studies report context-dependent protection against muscle wasting [42, 43]

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Supporting Research Another 2026 retrospective cohort study analysed data from January 2010 to January 2025, spanning across more than 90 healthcare organisations

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This dual oversight allows both teams to monitor liver function tests, metabolic markers, and gastrointestinal tolerance simultaneously rather than in silos
