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GLP-1 acts locally in the GI tract and via the vagus nerve, a key autonomic pathway that, when activated, further slows stomach emptying

[DOI] [PubMed] [Google Scholar] 61.Zhong J., Rajagopalan S

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d-allulose protects against diabetic nephropathy progression in Otsuka Long-Evans Tokushima Fatty rats with type 2 diabetes
First-generation short-acting agents (exenatide and lixisenatide), with twice-daily or once-daily administration provided proofs of concept for incretin-based therapy but required frequent injections and offered modest efficacy

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