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But, if you have access to both, we would recommend the following: If your health would benefit from the higher percentage weight loss (15-20%) of Zepbound / tirzepatide, and you have not had a cardiac event, Zepbound offers modestly more weight loss with fewer side effects

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Role of glucagon-like peptide (GLP-1) on vessel wall integrity The incretin hormone glucagon-like peptide-1 (GLP-1) is produced and secreted in the intestine upon food intake

6 For most people on Wegovy, this wont be a clinical concern, but its worth protecting bone density during weight loss

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