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Is the formulation scientifically sound

Upon food ingestion and its subsequent entry into the small intestine, intestinal L-cells undergo posttranslational processing of the proglucagon gene, leading to the production of glucagon-like peptide-1 (GLP-1), a potent incretin peptide hormone 9
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Merely switching from q1wk to q2wk decreases the peak drug concentration by 28% for tirzepatide and 38% for semaglutide (see the Data S1)

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For patients with established HF and a reduced left ventricular ejection fraction (LVEF), the LIVE and FIGHT trials studied the effect of 2-year liraglutide use [90, 91]
