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Treatment with oxyntomodulin, exendin-4 and GLP-1 increased neurite length in cultured neurons compared with controls, but did not stimulate calcium influx directly, or affect capsaicin responses

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The observations that GLP-1 receptor agonists exert anti-inflammatory actions in preclinical studies, taken together with case reports linking improvements in psoriasis with GLP-1 receptor agonist therapy, illustrates the emerging clinical implications of non-classical anti-inflammatory actions of incretin-based therapeutics.

Covering Wegovy, Ozempic, Mounjaro, and more, this blog provides in-depth analysis of potential stomach issues, blood sugar impacts, pancreatitis risks, and more

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At low doses, GLP-1 agonists have been observed to reduce alcohol cravings, lower the frequency and volume of drinking and in some individuals produce a natural disinterest in alcohol altogether