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The FDA's overview of GLP-1 medications also highlights the importance of using these medications under appropriate medical supervision
When that process isnt possible, he notes that seeking specialized care may help
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Simply put, the more muscle you have, the more calories your body burns each day just to maintain basic functions like breathing and circulation
The gut microbiome also shifts during GLP-1 therapy
Genetic and pharmacogenomic studies implicate GLP1R , ARRB1 (-arrestin-1), and other loci in contributing to interindividual variability (225)
