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Phylum-level analysis (Figure S1D) revealed that the VPA-ASD group was dominated by Pseudomonadota (Proteobacteria), with elevated Deferribacterota and Campylobacterota, and severe depletion of Bacteroidota and Verrucomicrobiota

Furthermore, alternative splicing is the promoter that generates a variety of structural and functional diversity proteins [43]
DOI 10.1016/j.jtemb.2004.03.007

SELENOP maintains the activity of glutathione peroxidase 4 (Gpx4) by binding to LRP-1, preventing lipid peroxidation and ferroptosis, both of which contribute to neurodegeneration in AD [15]

Dynamic transcriptional responses to stress, mediated by factors like ATF4 and XBP1, also play a central role by balancing adaptive mechanisms with apoptotic pathways (Kleiber et al., 2021)

Given these higher rates of nutrient utilization, metabolic flux through mitochondrial pathways and the associated ROS production can often be higher in cancer cells