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CrossRef STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of Hypercholesterolemia Emmelie Cansby, Elin Magnusson, Esther Nuez-Durn, Manoj Amrutkar, Matteo Pedrelli, Paolo Parini, Jenny Hoffmann, Marcus Sthlman, Brian W

Safety-first, evidence-forward guidance for GLP-1s

Araj, S

You want people to be healthy, Santoro says, but are we stressing women out by forcing them to lose weight and to go on a pretty rigorous weight-loss protocol thats actually not helping? GLP-1 drugs may offer a more effective alternative, she says, promoting weight loss with less psychological strain

Ethics declarations Conflict of Interest The authors declare no competing interests

3.1 Innate and adaptive immune response In rat models of systemic inflammation, a GLP-1 RA, exendin, significantly lowered pro-inflammatory cytokine levels, including IL-1, IL-6, TNF-, and interferon-gamma (IFN-) (41)