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Since the EGFR C797S mutant protein confers resistance to the inhibitor osimertinib, PROTAC could be a promising alternative treatment for lung cancer patients harboring this mutation 137

The combination therapy also showed concomitant protection against cardiovascular complications [47]

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In the redox reaction catalyzed by glutathione peroxidase (GPX), GSH is converted to glutathione disulfide (GSSG), which can be reconverted to GSH by the enzyme glutathione reductase (GR)

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