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Mitochondria: the ketogenic dietA metabolism-based therapy

10.1111/j.1471-4159.1990.tb02325.x J Neurochem
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asymptomatic patients are stage I, those with intermittent claudication (IC) are stage II, with rest pain stage III, and with trophic lesions stage IV [48]

This makes it a potential treatment option for those suffering from mood disorders

The role of the neuroendocrine and immune systems in thepathogenesis of depression
