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While IGF-1 has important physiological functions, elevated levels carry potential concerns including increased cell proliferation that may support tumor growth in individuals with cancer or pre-cancerous conditions, accelerated aging processes through growth pathway activation, potential cardiovascular effects with chronic elevation, and metabolic consequences including effects on glucose and lipid metabolism

One important limitation: the clinical weight loss results were modest

(wada-ama.org) If youre tested in sport, this matters regardless of your intent

Anh, F

Effect of administration route on the pharmacokinetics of cobalamin in elderly patients: a randomized controlled trial