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It highlights emerging evidence, safety considerations, and equity challenges that position GLP-1 RAs as a promising public health strategy for this high-risk population.

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A reduction in GLP-1 expression was observed in DIO mice with mitochondrial stress responses in the colon enterocytes

Glucagon-like peptide-1 (GLP-1) receptor agonists function like the incretin hormone GLP-1 that is released into the intestine after consumption of food

Stopping GLP-1 receptor agonists 14 days prior to total hip or knee arthroplasty may reduce several key risk factors associated with anesthesia complications, according to results presented here.“Specifically for semaglutide, stopping that medication 14 days before surgery is safest based upon the dataset that we have to minimize your risks with anesthesia, especially when