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Incretin-based therapies for treatment of obesity The concept of incretin-based treatment of overweight and obesity was driven by the effect of native GLP-1 and GLP-1R agonists on appetite and satiety in combination with an observed loss in body weight in trials investigating liraglutide for the treatment of type 2 diabetes [27]

Zydus is developing ZYOG1, an oral GLP-1 receptor agonist intended for type 2 diabetes and obesity

"Just give people the drugs," she said

The figure summarizes FDA-approved and investigational non-diabetes indications for GLP-1RA

Nature reviews Gastroenterology & hepatology , 15 (1), 11-20

Steppan, C