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10.3390/ijms20225549 104 WangH.LiuC.ZhaoY.GaoG

Different investigations have referred to the safety of polyphenols at high doses (up to 8 g per day), but a clear dose has not yet been determined or decided

Biochem Biophys Acta 1830:33173328 Schulz JB, Lindenau J, Seyfried J, Dichgans J (2000) Glutathione, oxidative stress and neurodegeneration

(2007) showed for the first time in an in vivo model that high hepatic GSH (1.5-fold), cysteine (15-fold), and glutamate cysteine ligase activity (1.5-fold) levels correlate with increased telomerase activity

GSH conjugation to a toxic substance, such as a halogenated alkene, may result in a more polar molecule.

The mean peak level of adducts for subjects in this study was 0.4 nmol/mL (0.2 nmol/mL)
