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Role for DNA methylation in the control of cell type specific maspin expression

Olaparib is a compound that effectively inhibits PARP1 and PARP2, binding to the catalytic domain and preventing the transfer of ADP-ribose units from NAD + to target proteins, thus lowering NAD + consumption 160,161

ASNase, the first-line chemotherapeutic agent for ALL, functions well as an anti-AML agent [27]

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PMID: 29986520

TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: Molecular mechanisms, cellular processes, and emerging therapeutic opportunities
