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If large swathes of the general public start taking them off-label for weight loss and then we find out years later that there are bad side effects, it could be a real issue. Rethinking long-term weight management strategies to overcome cost barriers Yet another dimension affecting the use of GLP-1RAs is cost

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Semaglutide is a glucagon-like peptide 1 receptor agonist used to improve metabolic health and support weight loss as an adjunct to lifestyle changes

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[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study