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Researchers have observed modulatory effects on brain reward pathways, potentially reducing symptoms of depression, anxiety, and even curbing addictive behaviours such as alcohol or food cravings

10.1016/j.bbamem.2022.184027 38 HurE

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Billings noted that basal insulin and GLP-1 combinations led to low rates of these side effects throughout clinical trials

While clinical trials report gastrointestinal symptoms in 1544% of users, formally diagnosed gastroparesis appears uncommon
References Htike ZZ, Zaccardi F, Papamargaritis D, Webb DR, Khunti K, Davies MJ
