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Am J Respir Crit Care Med 164:18601866

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Breathing Capacity Drops Many smokers experience: Shortness of breath on exertion Wheezing Reduced stamina persistent phlegm HRCT scans often demonstrate early emphysema, airway obstruction, and bronchiolar thickening

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Nicotine and other chemicals also affect heart rhythm and pump function

[3] Most exhibitors still declined to show Arbuckle's films, several of which are now considered lost