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Williams says
This is because the BBB is a highly selective biological barrier composed of specialized types of endothelial cells that form a tightly controlled barrier, protecting the brain from the influence of external substances

PYY3-36 as an anti-obesity drug target

doi: 10.1210/jc.2015-3291
BBR is noted for its low toxicity and a range of therapeutic benefits, including anti-inflammatory, antioxidative, anti-diabetic, and anti-tumor properties [129]

Research suggests that certain natural compounds in coffee, called polyphenols, might support the release of GLP-1
