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In a median follow-up period lasting 19.2 years, having a UIC higher than 400 g/L indicated an increased risk (HR = 1.19) for all-cause mortality

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All these circumstances decrease the amount of NO and cause the loss of endothelial function

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In line, ETC complex protein levels were reduced in mutant FoB compared to controls (Supplementary Fig

In conclusion, the present study demonstrates that the diurnal rhythm of GC signaling is involved in the control of the bladder peripheral clock and a mismatch between the central and peripheral bladder clocks decrease the diurnal rhythm of volume voided per micturition