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While one potential side effect of pioglitazone is weight gain, DeFronzo said that rather than being a negative association, this shows the drug is working to mobilize fat to less harmful areas of the body

Success will depend on: Manufacturing scale

GLP-1s work via the endocrine system and may trigger malignancies in these patients

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Semaglutide, better known by brand names such as Wegovy, is a glucagon-like peptide-1 (GLP-1) receptor agonist drug that has been approved by the U.S

In contrast, cell-based studies in human hepatic stellate cells and hepatocytes provide a more nuanced picture