side effects of glp-1 drugs Updated Ranking and Receptor Agonists When glp 1 drug side effects

Other combinations of entero-pancreatic hormones including cagrisema (GLP-1/amylin RA) and the triple agonist retatrutide (GLP-1/GIP/glucagon RA) have also progressed to phase 3 trials as obesity treatments and early data suggests that may lead to even greater WL than tirzepatide

2221-2232, Rakipovski, Gnaj, et al

Other incretin projects : Lilly acquired Protomer Technologies in late 2024 specifically to get access to novel glucagon/GLP-1 peptides and oral incretins

Kidney transplant patients taking GLP-1 drugs had a 49% greater risk of developing diabetic retinopathy, a potentially blinding condition caused by damage to the light-sensitive tissue lining the back of the eyes

reported a significantly increased risk of aspiration pneumonia in GLP-1 RA users undergoing gastrointestinal endoscopy, especially with propofol sedation, likely due to impaired airway protection reflexes [110]

[DOI] [PubMed] [Google Scholar] 27.Holt M.K., Llewellyn-Smith I.J., Reimann F., Gribble F.M., Trapp S