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Some people, on the other hand, find the abdomen to be a less painful injection site than the thigh

One of the main causes of the excess cardiovascular risk in diabetics is the coexistence of hypertension

These favorable effects may contribute to the observed survival benefits in patients with type 2 diabetes and concomitant AKD

Wharton, S., Batterham, R

[DOI] [PMC free article] [PubMed] [Google Scholar] 187.Schiavo L., De Stefano G., Persico F., Gargiulo S., Di Spirito F., Griguolo G., Petrucciani N., Fontas E., Iannelli A., Pilone V

The action on kidneys appears to be directly through the effects also on renin-secreting cells of the juxta-glomerular apparatus, whose stimulation may lead to increased natriuresis and reduce hyperfiltration, and indirectly by the reduction of angiotensin II levels, the increase in nitric oxide with consequently endothelial vasodilation and the improvement of risk factors of kidney disease (hyperglycemia, hypertension, obesity) ( Figure 2 )