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Hold, dont leap

Rats receiving vagotomy do not reduce food intake in response to peripherally injected GLP-1 indicating that vagal afferent nerves are needed to relay peripheral GLP-1 signals to higher brain regions to regulate feeding (Abbott et al., Phox2b-Cre Glp1r flox/flox ) (Sisley et al., Phox2b-Cre Glp1r flox/flox mice fed a HFD reduced food intake, body weight, and adiposity suggesting that the PNS is not required for liraglutide to mediate its effects on energy metabolism

Your anesthesia team will ask about your GLP-1 use during preoperative assessment to plan accordingly

Some people seem to be particularly responsive to GLP-1 therapy, potentially due to genetic factors affecting GLP-1 receptor density or sensitivity

Its primary functions include: Stimulating Insulin Release: GLP-1 tells the pancreas to release insulin, which helps your cells absorb glucose from the bloodstream, thereby lowering blood sugar levels after a meal