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Curcumin penetration into the cerebral cortex and striatum was significantly enhanced, with delivery levels at 0.45 MPa acoustic pressure being 1.45-fold higher than at 0.31 MPa

J Nutr 135(12):27802785 Benarrosh A, Garnotel R, Henry A, Arndt C, Gillery P, Motte J, Bakchine S (2013) A young adult with sarcosinemia

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Moreover, the inflammatory response triggered by blood in the brain tissue can exacerbate oxidative stress