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In preclinical models, co-administration of bimagrumab or dual myostatin/activin A inhibitors with GLP-1R agonists preserves or increases muscle mass while enhancing fat loss, resulting in improved body composition and metabolic outcomes compared with GLP-1R agonist monotherapy [176]
doi: 10.1002/path.5056
Differential effects of PPAR- activation versus chemical or genetic reduction of DPP-4 activity on bone quality in mice
Inoue, H
doi: 10.1016/j.jacc.2023.12.023
Lingvay, J
