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The systems were first energy minimized for 10,000 steps and then heated gradually from 0 to 310 K for 250 ps, using a Langevin thermostat with heavy atoms restrained at 10 kcal mol 1 2 in an NVT ensemble

648 In addition, the EpOMEs, but not DiHOMEs, promote hair follicle stem cycling and enhance hair growth, 649 and EpOMEs can induce colon tumorogenesis in vivo

Relationship to the GH-IGF-1 Axis Because this fragment does not appear to stimulate IGF-1 production in laboratory models, it provides researchers with a tool to study the IGF-1-independent aspects of GH signalling in metabolic biology

10.1007/s12079-010-0116-9

Statements Author contributions HZ and RM wrote the draft

Ill definitely reorder