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Therefore, recent guidelines recommend GLP-1 RAs for patients with T2DM, established or high-risk atherosclerotic cardiovascular disease, and/or chronic kidney disease for glycemic management and comprehensive cardiovascular risk reduction [6,7]

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This information is crucial for our prescribers to make informed decisions about treatment suitability

104 Cotadutide by AstraZeneca and efinopegdutide by Merck Sharp & Dohme are other GLP-1R/GCGR dual agonists

31 , 32 Los estudios clnicos ya han demostrado que la adicin de iSGLT2 a los iDPP4 mejora las concentraciones de glucosa con prdida significativa de peso, 33 , 34 y al tener en cuenta que los pacientes con diabetes mellitus tipo 2 tienen de base aumento del glucagn y de la gluconeognesis heptica, 35 - 39 se ven beneficiados con la administracin de AGLP1