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Titration: Increase to 0.5 mg once weekly for at least 4 weeks

Common side effects are usually mild and temporary

Whether this combination is recommended depends on your overall health, existing medical conditions and the outcomes your treatment aims to achieve

[12] NICE Clinical Knowledge Summaries for candidiasis and balanitis provide further guidance on management and when specialist referral may be needed

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For the AMPK and adipocytokine/adiponectin pathways, recurrent nodes included G6PC, PPARG, and PPARGC1A, genes central to hepatic glucose regulation, adipose metabolism, and mitochondrial function, pathways consistently linked to GLP1RA metabolic benefits