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(7) The claim may state that individuals with elevated blood total- or LDL-cholesterol should consult their physicians for medical advice and treatment

Morbidity and Mortality Weekly Report, 68(39), 865869

That helps prevent flavor fatigue and makes it easier to tell when a lot is fresher than the last one.

Breathing is also hampered because of the chemicals in cigarettes that harm the cells lining the eustachian tube (the tube that connects the middle ear to the back of the nose and throat)
The low prevalence of tobacco use in this study group may explain the absence of association between medical background and attempts to quit

Over time, this can lead to chronic gum issues, which may eventually progress to periodontal disease
