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10.1186/1742-2094-11-135 99 LiuY.ZhaoZ.GuoC.HuangZ.ZhangW.MaF.et al (2023)
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NAD+ is mainly synthesized from NAM by the rate-limiting enzyme Nam phosphoribosyltransferase (NAMPT) and degraded to Nam by NAD+-degrading enzymes in mammals [29]
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