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Figure 2 plots the three-dimensional surface of the RR values estimated from the model as a function of smoking prevalence between 1991 and 2020 and lag l, with l from 0 to 25 years

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Waters AJ, Shiffman S, Sayette MA, Paty JA, Gwaltney CJ, Balabanis MH

From the NIH website: Alcohol use disorder (AUD) is a medical condition that doctors diagnose when a patients drinking causes distress or harm