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Scientists are uncovering an unexpected potential for semaglutide, the active ingredient in popular weight-loss medications like Ozempic and Wegovy

Perreault, L., et al

Common side effects during the early weeks include: Nausea (the most frequently reported) Reduced appetite Mild abdominal discomfort or bloating Occasional diarrhoea or constipation These effects are usually mild to moderate and tend to diminish as the body adapts to the medication

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Here, we review the therapeutic effects of GLP-1 on depression from a variety of perspectives and highlight the promising, beneficial roles of GLP-1 as the therapeutic regulator of impaired neurogenesis, neuroinflammation, imbalance of neurotransmitter secretion, and synaptic dysfunction in the depressive brain

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